Komal Raina Selected Research

Grape Seed Extract

1/2019	Differential effect of grape seed extract and its active constituent procyanidin B2 3,3″-di-O-gallate against prostate cancer stem cells.
10/2014	Functional modification of adipocytes by grape seed extract impairs their pro-tumorigenic signaling on colon cancer stem cells and the daughter cancer cells.
8/2014	Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy.
1/2014	Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins.
1/2014	Procyanidin B2 3,3(″)-di-O-gallate, a biologically active constituent of grape seed extract, induces apoptosis in human prostate cancer cells via targeting NF-κB, Stat3, and AP1 transcription factors.
11/2013	Role of oxidative stress in cytotoxicity of grape seed extract in human bladder cancer cells.
7/2013	Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation.
6/2013	Differential effects of grape seed extract against human colorectal cancer cell lines: the intricate role of death receptors and mitochondria.
1/2013	Differential effect of grape seed extract against human non-small-cell lung cancer cells: the role of reactive oxygen species and apoptosis induction.
5/2008	Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice.

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Komal Raina Research Topics

Disease

43	Neoplasms (Cancer) 01/2022 - 09/2004
17	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 09/2004
11	Adenocarcinoma 01/2022 - 06/2007
10	Colorectal Neoplasms (Colorectal Cancer) 02/2021 - 09/2012
8	Body Weight (Weight, Body) 08/2012 - 06/2007
7	Carcinogenesis 01/2022 - 12/2007
7	Lung Neoplasms (Lung Cancer) 01/2017 - 09/2007
6	Carcinoma (Carcinomatosis) 01/2018 - 12/2007
5	Pancreatic Neoplasms (Pancreatic Cancer) 10/2020 - 07/2013
5	Neoplasm Metastasis (Metastasis) 01/2018 - 08/2008
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017 - 10/2012
3	Hypoxia (Hypoxemia) 12/2009 - 08/2008
2	Colonic Neoplasms (Colon Cancer) 10/2014 - 07/2014
2	Urinary Bladder Neoplasms (Bladder Cancer) 11/2013 - 12/2007
2	Inflammation (Inflammations) 07/2013 - 03/2013
2	Adenocarcinoma of Lung 06/2010 - 01/2009
2	Prostatic Intraepithelial Neoplasia 12/2008 - 11/2007
1	Fibrosarcoma 01/2022
1	Basal Cell Carcinoma (Rodent Ulcer) 01/2022
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2022
1	Skin Neoplasms (Skin Cancer) 05/2020
1	Melanoma (Melanoma, Malignant) 05/2020
1	Disease Resistance 01/2018
1	Adenoma (Adenomas) 07/2013
1	Polyps 07/2013
1	Starvation 05/2013

Drug/Important Bio-Agent (IBA)

20	Silybin (Lagosa)IBA 01/2022 - 09/2007
11	Grape Seed ExtractIBA 01/2019 - 06/2007
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2009
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2017 - 08/2008
4	Pharmaceutical PreparationsIBA 10/2020 - 01/2014
4	Phytic Acid (Inositol Hexaphosphate)IBA 01/2013 - 05/2008
4	Proliferating Cell Nuclear Antigen (PCNA)IBA 08/2012 - 12/2008
3	AzoxymethaneIBA 02/2021 - 07/2013
3	SilymarinIBA 05/2020 - 12/2007
3	Glucose (Dextrose)FDA LinkGeneric 09/2019 - 05/2009
3	Biomarkers (Surrogate Marker)IBA 07/2013 - 05/2009
3	CarcinogensIBA 01/2013 - 12/2007
3	NestinIBA 01/2012 - 01/2009
2	Gemcitabine FDA Link 10/2020 - 01/2018
2	Lactic Acid (Lactate)FDA LinkGeneric 09/2019 - 05/2009
2	procyanidin B2IBA 01/2019 - 01/2014
2	nintedanibIBA 01/2018 - 05/2017
2	CytokinesIBA 07/2013 - 01/2009
2	Cadherins (E-Cadherin)IBA 05/2013 - 12/2008
2	NF-kappa B (NF-kB)IBA 03/2013 - 01/2009
2	SmokeIBA 01/2013 - 12/2007
2	Cytotoxins (Cytolysins)IBA 01/2013 - 09/2007
2	NitrosaminesIBA 01/2013 - 12/2007
2	PhytochemicalsIBA 01/2013 - 09/2012
2	Hormones (Hormone)IBA 08/2012 - 09/2004
2	Drinking WaterIBA 12/2009 - 12/2007
2	Platelet Endothelial Cell Adhesion Molecule-1IBA 12/2009 - 08/2008
2	Matrix Metalloproteinases (MMPs)IBA 12/2008 - 08/2008
1	zinc-binding protein (zinc binding protein)IBA 01/2022
1	ZincIBA 01/2022
1	Dextrans (Dextran)FDA Link 02/2021
1	myristoylcarnitineIBA 02/2021
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 02/2021
1	PalmitoylcarnitineIBA 02/2021
1	Protein Kinases (Protein Kinase)IBA 09/2019
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 09/2019
1	Adenosine Monophosphate (AMP)IBA 09/2019
1	Biological ProductsIBA 09/2019
1	procyanidinIBA 01/2019
1	AntigensIBA 01/2019
1	Oxygen (Dioxygen)IBA 01/2018
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 05/2017
1	AnthracyclinesIBA 01/2017
1	fisetinIBA 01/2017
1	acacetinIBA 01/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2017
1	MucinsIBA 08/2014
1	Interleukin-4 (Interleukin 4)IBA 07/2014
1	InterleukinsIBA 07/2014
1	Transcription Factors (Transcription Factor)IBA 01/2014
1	ImmunosorbentsIBA 07/2013
1	Propidium (Propidium Iodide)IBA 07/2013
1	AnnexinsIBA 07/2013
1	EnzymesIBA 07/2013
1	AMP-Activated Protein KinasesIBA 07/2013
1	MicroRNAs (MicroRNA)IBA 07/2013
1	BromidesIBA 07/2013
1	Death Domain ReceptorsIBA 06/2013
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 05/2013
1	Phospholipids (Phosphatides)FDA LinkGeneric 05/2013
1	MethyltransferasesIBA 05/2013
1	Histone Deacetylases (Histone Deacetylase)IBA 05/2013
1	DNA (Deoxyribonucleic Acid)IBA 05/2013
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 03/2013
1	Calcibiotic Root Canal SealerIBA 01/2013
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2013
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 01/2013

Therapy/Procedure

13	Therapeutics 10/2020 - 09/2004
7	Chemoprevention 01/2018 - 06/2007
2	Drug Therapy (Chemotherapy) 01/2018 - 12/2009
1	Fecal Microbiota Transplantation 02/2021
1	Precision Medicine 01/2018
1	Oral Administration 07/2013
1	Molecular Targeted Therapy 01/2013